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Shanghai Avian H7N9 Distinct From Human
Recombinomics Commentary 13:00
April 7, 2013

The Harbin Veterinary Institute has released full sets of sequences from a pigeon, (A/Pigeon/Shanghai/S1069/2013), chicken (A/Chicken/Shanghai/S1053/2013), and environment (A/Environment/Shanghai/S1088/2013) from Shanghai and collected on April 2 or April 3, which would match samples cited in OIE reports.

Harbin and the Ministry of Agriculture are to be commended for the rapid release of these critical sequences. 

The sequences are closely related to the human H7N9 sequences (most closely related to the more recent human sequence (A/Shanghai2/2013, A/Anhui/1/2013, A/Hangzhou/1/2013) and all three have H7 Q226L as well as the 5 amino acid deletion in N9.

However, none have PB2 E627K and there is divergence in other internal genes, indicating these sequences were not the recent source of the human H7N9 cases.

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