Recombinomics | Elegant Evolution

Home Founder What's New In The News Consulting

H1N1 Consulting

Paradigm Shift

Viral Evolution

Intervention Monitoring

Vaccine Screening

Vaccine Development

Expression Profiling

Drug Discovery

Custom Therapies


Audio:Apr29 May2 May16 MAP RSS Feed twitter News Now                         


26th MERS-CoV Fatality In KSA Raises Concerns
Recombinomics Commentary 23:00
June 10, 2013

And fell asleep Aldhnin (48 years old), in the isolation room at the King Fahd Hospital in Hofuf (Al Ahsa), weeks ago, during which he tried to resist the virus, and despite the improvement of the health situation in the period of stay in the hospital, but his health finally relapsed. Abraham injured, ill «chronic renal failure» 3 years ago, and began washing stage two years ago, and got a chance kidney transplant 6 months ago, but they were unsuccessful, and he returned to the weekly laundry again.

The above translation describes the 26th MERS-CoV death in the Kingdom of Saudi Arabia (KSA).  This death increases the case fatality rate (CFR) for the confirmed cases in KSA to 65% (see map).  However, only seven of the confirmed cases that are alive have been discharged.  The other seven remain hospitalized and most are in critical condition.  The case fatality rate for the confirmed cases with outcomes is 78%.

Both of these rates are dramatically different than the CFR for onward transmission cases in Europe or Africa, raising concerns that KSA detection is largely limited to hospitalized cases with severe pneumonia where the vast majority die.  Milder cases are largely missed, either because viral RNA levels in the upper respiratory tract are low or samples from the lower respiratory tract are not collected because milder cases do not produce sputum.

The above case was from the large cluster of cases in Hofuf, Al Hasa who were infected while being treated for underlying conditions like renal failure of diabetes complications.  Many of these patients were already dead when confirmed, while most that were alive a month ago have since died, as described above for the latest confirmed death.

The high case fatality rate for the cases in KSA raises concerns that the number of mild cases is orders of magnitude higher than the fatal cases, and the upcoming Ramadan and Hajj events will lead to infections of pilgrims, followed by dramatic spread worldwide.

Media Link

Recombinomics Presentations

Recombinomics Publications

Recombinomics Paper at Nature Precedings

Home | Founder | What's New | In The News | Contact Us

© 2013 Recombinomics.  All rights reserved.