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Paradigm Shift Intervention Monitoring
trH3N2 Cases Linked To Fryeburg Fair
• A male
child became ill with influenza-like symptoms (fever, cough, chills and
body aches) on October 22, 2011. The child continues to recover from
Recombinomics has discussed this case with the Maine CDC and Maine Department of Agriculture who have confirmed that both Maine cases attended the same agricultural fair and earlier reports indicated the first case attended a fair in the week prior to disease onset. Two fairs in Maine match those dates (Cumberland fair from September 25 to October 1 and Fryeburg Fair from October 2 to October 9). The contact for one of the cases was a pig scramble and both fairs had pig scrambles in October. However the preponderance of evidence, indicates the swine “exposure” fair was the Fryeburg fair, which ended on October 9, well in advance of disease onset for the second Maine case, casting serious doubt on the fair exposure as a source for the trH3N2 infection..
Moreover, the sequences
of the Maine isolates are virtually identical, casting doubt on a swine
origin for either case. Initial testing by the Maine Department
of Agriculture of symptomatic swine from the fair have been negative
for any SOIV, although the videographer filming the Fryeburg pig
scramble was coughing
throughout the 6:41 upload.
The absence of suspicion for human-to-human transmission may be linked to earlier comments from the Maine CDC who issued an advisory claiming that all prior 2011 trH3N2 cases had a swine exposure, which was not true for the first case in Indiana (2M, A/Indiana/08/2011) or the epidemiologist who indicated no thought has given for human to human transmission, which is not supported the identical constellation of genes in all seven human cases, which has not been reported in swine in Maine, Indiana, Pennsylvania, or anywhere in the world.