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CDC Again Cites Swine Exposure In Request for trH3N2 Samples
Recombinomics Commentary 18:25
November 24, 2011

Although swine exposure was not associated with the three cases described in this report, because most previous cases of human infection with S-OtrH3N2 viruses have occurred in patients who reported swine exposure before illness onset, clinicians should consider swine-origin influenza A virus infection in the differential diagnosis of patients with febrile respiratory illness who have had contact with swine. It is anticipated that commercially available diagnostic tests, including point-of-care rapid tests, will detect infection with the S-OtrH3N2 virus; however, these tests will not differentiate S-OtrH3N2 from seasonal influenza A viruses. Clinicians who suspect swine influenza virus infections in humans should treat with oseltamivir when indicated (7), obtain a nasopharyngeal swab from the patient, place the swab in viral transport medium, and contact their state or local health department to facilitate transport and timely diagnosis at a state public health laboratory, using the CDC RT-PCR assay cleared by the Food and Drug Administration. CDC requests that state public health laboratories send all suspected novel influenza A specimens, such as these S-OtrH3N2 viruses, to the CDC Influenza Division's Virus Surveillance and Diagnostics Branch Laboratory.

The above request for samples is from the latest CDC MMWR on trH3N2 transmission.  Like the first report, which described the first two cases with the novel trH3N2 constellation with an M gene from H1N1pdm09, this report confuses the need for samples from children, with the CDC’s need to maintain its charade on the linkage between trH3N2 infections and swine “exposure”.

The above comments acknowledge the technical difficulties in identifying trH3N2, which has led to a heavy bias on testing, which created the illusion of an epidemiological link between trH3N2 infections and swine exposure, which in fact is a link between trH3N2 testing and swine exposure.

The CDC should end its charade (including using "S-OtrH3N2" for a novel trH3N2 which has nothing to do with swine) and simply test (including sequence) the large number of influenza  A positve samples from patients under 10 years of age, and issue a request for such samples with no swine exposure.

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