Recombinomics | Elegant Evolution

Home Founder What's New In The News Consulting

H1N1 Consulting

Paradigm Shift

Viral Evolution

Intervention Monitoring

Vaccine Screening

Vaccine Development

Expression Profiling

Drug Discovery

Custom Therapies


Audio:Oct21 Nov11 Nov18 Dec16 RSS Feed twitter News Now                         


UK H1N1 ICU Cases Spike To 738
Recombinomics Commentary 17:30
December 30, 2010

Last week there were 460 people in intensive care, which has now jumped to 738. There are more than 3,600 intensive care beds with contingency plans in place to double this if necessary.

The above comments reflect the serious nature of the H1N1 outbreak in the UK.  Last season, the peak number was 180, and at that level there was a shortage of ECMO machines.  The jump to 460 last week raised serious questions about the ability to deliver appropriate health care to the severe cases.  There are only 20 machines in the entire country, and each patient requires 5 days to three weeks, so on average about 2 machines become available each day.  However, the jump from 302 severe cases on December 20 to 460 on December 24, to 738 on December 30 indicates the freeing of 2 machines per day, falls far short of the need.

Similarly, these increases severely impact ICU beds, which are undoubtedly full at this time with the exploding numbers of flu cases, in addition to other conditions and procedures that require ICU beds.  Thus the necessity for doubling the ICU beds is already abundantly clear, but the plans to increase ECMO machines are not.

Moreover, the latest HPA report cites increases in Tamiflu resistance, which will undoubtedly increase the number of severe and fatal cases.
Initial sequence data from four patients demonstrate an evolution via recombination away from the current vaccine, as well as immunity elicited toward H1N1 from last season. 

The earlier data on fatal cases indicated a majority did not have pre-existing conditions, and the vaccination uptake in those under 65 who do not have risk factors is abysmal.  Similarly, the latest series of agency comments, which ignore the increasing number of severe and fatal cases in previously healthy young adults. increases concerns that the serious nature of the current situation is being lost in sound bites and head pats.

Media link

Recombinomics Presentations

Recombinomics Publications

Recombinomics Paper at Nature Precedings

Home | Founder | What's New | In The News | Contact Us

© 2010 Recombinomics.  All rights reserved.