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Reported US Pediatric Flu Deaths Increase To 38
Recombinomics Commentary 01:30
January 15, 2013

Recent updates have increased the number of reported US adolescent flu deaths to 38, almost double the 20 cases reported by the CDC in the week 1 FluView.  Most of the 38 cases have been lab confirmed (see list below) and most that have not been confirmed have been reported in 2013 and will soon be confirmed.  Fourteen on the 18 cases not reported in FluView have been reported in the media or state lab reports in 2013.

This large increase indicates the weekly number will be significantly higher than the two cases reported for week 1.  In addition to the reported adolescent deaths, the dramatic rise in adult deaths and hospitalizations indicate the adolescent deaths will rise significantly, dips due to holidays notwithstanding.

These recent increases are largely due to H3N2 and the poor match with the current vaccine.  Although the Victoria/361 sub-clade is dominant, genetic changes associated with low reactors are common and increasing, especially for those found in A/Iowa/14/2012, which includes the abolishment of the glycosylation site at position 126 due to T128A.

FluView pediatric cases
Wk   #    Location
01    2    KS TX
52    2    MI NY
51    8    AR FL ME MI(2) TX WA WI
50    2    NJ
49    1    TX
48    3    IN FL SC
46    1    TX
41    1    TN

Pediatric deaths not in FluView
02    7    MA NE NY TX* TX* OH* OH
01    7    MI* MN* NE* NY* PA SC* TX*
52    1   IN*
50    2    CO*  CO*
48    1    OH

* = Lab Confimed

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