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LaPorte County Fair H3N2v Cluster Matches WV/UT Cases
Recombinomics Commentary 15:20
July 27, 2012

The CDC has released a full set of sequences (at GISAID) from one of the cases at the LaPorte County Fair in Indiana (A/Indiana/07/2012 collected on July 16, 2010).  The sequence is closely related to the other 2012 case (A/Utah/10/2012) and the most recent human sequences from 2011 (A/West Virginia/06/2011 and A/West Virginia/07/2011) which have an N2 which is distinct from the first 10 human cases in 2011.

The detection of this sub-clade once again raises concerns that this sub-clade is transmitting in humans.  Public swine sequences collected since the West Virginia cluster are heavily weighted toward the earlier sequence (13/15 matches) although one of the two swine matches with recent human cases is from Indiana (
A/swine/Indiana/A01203509/2012)collected on May 5, 2012).

The CDC is commended for the rapid release of these important sequences.

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