Novel Influenza Case In Week 30 MMWR
August 4, 2011
Novel influenza A infection virus *** -
2 0 4 43,774 2 4 NN
The above line is from the preview
of the MMWR
week 30 report. The preview does not contain the detail for
the footnote, which usually is available around noon EST on the
Thursday before the Friday report.
However, it is likely that the “Novel influenza A” case will be another
confirmed case in 2011, based in part by the release of sequences
yesterday by the CDC demonstarting the production of a trH3N2
vaccine target, various constructs of A/Minnesota/11/2010, the
second trH3N2 case in Minnesota last year.
Prior to today’s report, there were nine trH3N2
cases reported in the United States, including two from Minnesota
and two from Pennsylvania. All reported sequences have D225G,
which may lead to a higher detection frequency when eggs are used to
Recent sequences from the CDC, including the new
pandemic H1N1 (trH1N1) vaccine target, A/South Carolina/02/2010,
have changes at position 225 and 226 (SC/02/10 has Q226R).
Today’s report raises concerns that the number of trH3N2 cases in the
United States is far higher that the nine cases reported prior to today.
More detail on additional cases under investigation would be useful.
at Nature Precedings